The Fortescue Metals Group loaded vessel departed the port on late Wednesday morning, 1 March 2017.
The vessel loaded a total of 270,006 tonnes and departed at a record sailing draft of 19.95 metres.
The largest single shipment beats the previous record set by the vessel CSB Years in April 2015 which loaded a total cargo of 264,858 tonnes.
It also beats the previous maximum sailing draft of 19.67 metres set by the vessel Abigail N in February 2015.